Mariamena Arbitrio Selected Research

LNA-i-miR-221

9/2020	Development and validation of bioanalytical methods for LNA-i-miR-221 quantification in human plasma and urine by LC-MS/MS.
12/2019	Allometric Scaling Approaches for Predicting Human Pharmacokinetic of a Locked Nucleic Acid Oligonucleotide Targeting Cancer-Associated miR-221.
6/2016	Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates.

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Mariamena Arbitrio Research Topics

Disease

18	Neoplasms (Cancer) 06/2022 - 01/2013
8	Multiple Myeloma 08/2021 - 08/2011
4	Genomic Instability 01/2021 - 01/2019
2	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 06/2022 - 01/2021
2	Ovarian Neoplasms (Ovarian Cancer) 05/2022 - 10/2009
2	Rare Diseases (Rare Disease) 01/2021 - 03/2020
2	Drug-Related Side Effects and Adverse Reactions 12/2020 - 03/2020
2	Fabry Disease (Fabry's Disease) 12/2017 - 12/2016
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021
1	Paraproteinemias (Monoclonal Gammopathy) 01/2021
1	Melanoma (Melanoma, Malignant) 11/2020
1	Lung Neoplasms (Lung Cancer) 11/2020
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Disease Progression 12/2017
1	Inflammation (Inflammations) 01/2016
1	Exanthema (Rash) 01/2016
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2016
1	Colorectal Neoplasms (Colorectal Cancer) 11/2011
1	Osteonecrosis (Kienbock's Disease) 08/2011

Drug/Important Bio-Agent (IBA)

7	Biomarkers (Surrogate Marker)IBA 03/2022 - 09/2016
6	MicroRNAs (MicroRNA)IBA 03/2022 - 09/2015
6	Pharmaceutical PreparationsIBA 01/2022 - 11/2011
4	EnzymesIBA 01/2022 - 01/2016
3	Biological ProductsIBA 01/2022 - 10/2018
3	LNA-i-miR-221IBA 09/2020 - 06/2016
2	AntigensIBA 06/2022 - 01/2021
2	PlatinumIBA 05/2022 - 10/2009
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2019
2	Monoclonal AntibodiesIBA 03/2021 - 01/2021
2	Immune Checkpoint InhibitorsIBA 03/2021 - 11/2020
2	locked nucleic acidIBA 06/2020 - 12/2019
2	Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA 01/2019 - 11/2011
2	GalactosidasesIBA 12/2017 - 12/2016
1	CytokinesIBA 06/2022
1	Glycoproteins (Glycoprotein)IBA 06/2022
1	Carboplatin (JM8)FDA LinkGeneric 05/2022
1	Lenalidomide (CC 5013)FDA Link 08/2021
1	AntibodiesIBA 03/2021
1	Chimeric Antigen ReceptorsIBA 03/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 12/2020
1	OligonucleotidesIBA 12/2019
1	TrabectedinIBA 01/2019
1	taxaneIBA 01/2019
1	DNA Ligase ATPIBA 01/2019
1	Drug Receptors (Drug Receptor)IBA 12/2018
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 12/2017
1	mouse MIRN29 microRNAIBA 12/2017
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2016
1	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 01/2016
1	Cholecalciferol (Vitamin D3)FDA Link 01/2016
1	130-nm albumin-bound paclitaxelIBA 01/2013
1	Albumin-Bound Paclitaxel FDA Link 01/2013
1	Irinotecan (Camptosar)FDA LinkGeneric 11/2011
1	Member 1 Subfamily G ATP Binding Cassette TransporterIBA 11/2011
1	Zoledronic Acid (Zometa)FDA Link 08/2011
1	PPAR gammaIBA 08/2011

Therapy/Procedure

6	Therapeutics 01/2022 - 06/2016
5	Immunotherapy 06/2022 - 12/2018
2	Precision Medicine 01/2022 - 01/2022
1	Enzyme Replacement Therapy 12/2017